members.andrew reid | ||||||
profile | top | |||||
Current position : Birthplace: Alma mater: Field of study: |
Ph.D. student Memorial University of Newfoundland (B.Sc., M.Sc.) Behavioural Neuroscience |
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research interests | top | |||||
Human brain lesion analysis using a primate connectivity database. My main PhD project will be to apply the Macaque monkey brain connectivity data collated in the CoCoMac database to three-dimensional human brain lesion data obtained through structural and functional magnetic resonance imaging (MRI), in order to predict the functional effects of these lesions. The aim of this project is to demonstrate the possibility of using a computer database compiling a large number of anatomical research findings, to successfully predict the high-level functioning of neural tissue, and in particular the effects of specific tissue lesions upon this functioning. Generally speaking, such a predictive model may prove to be a useful and effective tool clinically, in that it can be used to guide diagnostic evaluation of a specific brain lesion. It might also prove valuable as a research tool, enabling the generation of specific testable hypotheses about the functioning of particular brain structures or networks. |
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Modelling and visualization of neuroscientific data. A further interest of mine is to develop an open-source, extensible, Java-based environment to both model and visualize brain structure and function. This environment will include database functionality, including connections to CoCoMac and other publicly available neuroscientific datasets. The development of this tool is intended to provide a number of capabilities, including flexible static and dynamic modelling at various scales, and visualization of structures, connectivity, and model output. An online interface allowing visualization of various types of neuroscientific data, registered to a template model, is also in development. New: the planned release date for the beta version of what I am tentatively calling the modelGUI project is 30 June, 2010. A pre-release version is now available; see the new Wiki site for details. |
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Relating cortical thinning and white matter degeneration. Using a large dataset of imaging data obtained from elderly subjects with various degrees of white matter degeneration, we intend to investigate the relationship of such degeneration to cortical thinning patterns revealed through advanced imaging techniques developed at the McConnell Brain Imaging Center at McGill University. Using such comparisons may provide important insights into the functional organization of the brain, as well as better defining the patterns of age-related neurodegeneration. |
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curriculum vitae | top | |||||
Research Career | ||||||
1998 - 2003 | Studied
Psychology (Behavioural Neuroscience) at Memorial University of Newfoundland,
St. John's, Newfoundland, Canada |
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2003 | Awarded
B.Sc. (hons) in Psychology (Behavioural Neuroscience)
from Memorial University. Honours
project involved behavioural and immunohistochemical data collection
in a rat olfactory learning paradigm (McLean
et al.) |
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2003 - 2006 | Studied Experimental Psychology (Behavioural Neuroscience) at Memorial University | |||||
2007 | Awarded
M.Sc. in Experimental Psychology (Behavioural Neuroscience)
from Memorial University. Masters
thesis involved in vivo electrophysiological data collection in a
rat dentate gyrus LTP paradigm (Harley
et al.) |
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Teaching and Supervision | ||||||
2006 | Teaching
Assistant, Memorial University. Involved supervising, advising,
and grading ~100 second-year Psychology students, in the seminal semester
of a new course entitled "Mind and Brain". |
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2007 - present | Laboratory
Assistant, University Medical Center, Radboud University, Nijmegen,
Netherlands. Involved supervising and assisting first-year medical students
with various laboratory sessions. |
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Memberships | ||||||
2005, 2009 | Society for Neuroscience | |||||
2007-present | Organization for Human Brain Mapping | |||||
Awards | ||||||
2007 | Canadian Psychological Association Certificate of Academic Excellence - Masters Thesis | |||||
2009 | Organization
for Human Brain Mapping Editor's
Choice Award (for Reid et al., 2009:
Optimization of cortical hierarchies) |
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publications | top | |||||
Peer-reviewed Articles | ||||||
Bojak I, Oostendorp TF, Reid AT, Kötter R (2010). Connecting Mean Field Models of Neural Activity to EEG and fMRI Data. Brain Topography (in press). |
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Reid AT, van Norden AGW, de Laat KF, van Oudheusden LJB, Zwiers MP, Evans AC, de Leeuw FE, Kötter R (2009). Patterns of cortical degeneration in an elderly cohort with cerebral small vessel disease. Human Brain Mapping (in press). [pre-print version | link] |
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Reid
AT, Harley CW (2009). An associativity requirement for
locus coeruleus-induced long-term potentiation in the dentate gyrus of
the urethane-anesthetized rat. Experimental Brain Research. [link] |
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Reid
AT, Krumnack A, Wanke E, Kötter
R (2009). Optimization of cortical hierarchies with continuous
ranges and scales. Neuroimage. 47(2): 611-7. [pre-print
version | link] |
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Bojak I, Oostendorp TF, Reid AT, Kötter R (2009). Realistic mean field forward predictions for the integration of co-registered EEG/fMRI. BMC Neurosci. 10: L2. |
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Bezgin
G, Reid AT, Schubert D, Kötter R (2008). Matching
spatial with ontological brain entities using integrated Java tools for
visualization and database access. Neuroinformatics. 7(1): 7-22.
[link] |
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Kötter
R, Reid AT, Krumnack A, Wanke E, Sporns O (2007). Shapley
ratings in brain networks. Frontiers in Neuroinformatics. 1:
2. [link] |
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Theses | ||||||
2003 | BSc.
(Hons) Thesis: NMDA phosphorylation in olfactory preference
learning: a critical step in neuronal plasticity? |
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2006 | MSc.
Thesis: An associativity requirement for noradrenergic
dentate gyrus long-term potentiation in the urethane-anesthetized rat
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Presentations | ||||||
November 2005 |
Society
for Neuroscience Annual Meeting, Washington, D.C. Poster presentation:
Unpaired perforant path and locus coeruleus activations only transiently
potentiate the evoked dentate gyrus population spike. |
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June 2008 |
Organization
for Human Brain Mapping Annual Meeting, Melbourne, AU. Poster
presentation: Age-related thinning of cortical grey matter. |
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October 2009 |
Helmholtz Alliance on Systems Biology Meeting, Heidelberg, DE. Short talk: Optimization of cortical hierarchies with continuous scales and ranges. |
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