members.rolf kötter  

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Chair, Section Neurophysiology & Neuroinformatics

Essen, Germany

Essen, Wien, Wuhan, Manchester, Montpellier, London

Medicine, Anatomy, Neuroinformatics

research interests top
   

I want to find out "how the brain works" and was attracted by the neural network models of the 1980s. Realizing that those were only sketches of the real brain and its function I became interested in the heterogeneity of the connections between neurons, as well as of entire brain areas. 

My group now focusses on the following aspects of brain connectivity:

  • Mapping the microcircuitry of the cerebral cortex using our development of the flash-induced release of caged transmitter substances
  • Collating the macrocircuitry of the cerebral cortex with advanced neuroinformatics tools for subsequent mapping and comparison with functional data
  • Systems approaches to modelling and analysis of network properties for multi-scale integration of structural and functional data modalities
 
curriculum vitae top
   
Research Career
 
1986 - 1989
Doctoral thesis in the laboratory of "O.-E." Brodde with a combined pharmacological, biochemical, and physiological characterization of alpha adrenoceptors.
1987 - 1988 Advanced studies in Neurology at the National Hospital Queen Square, London.
1989 - 1990 Joined the group of Günther Palm to specialise in Neuroinformatics.
1990 - 1994
Research fellow at the Dept. of Anatomy & Structural Biology, University of Otago in Dunedin, New Zealand, working with Jeff Wickens and Robert Miller on computer models of striatal mechanisms.
1994 - 1996
Helmholtz scholarship at the C. & O. Vogt Brain Research Institute headed by Karl Zilles starting the Computational | Systems | Neuroscience group.
2002
Habilitation on "Structural determinants of cortical information processing" using a combination of morphological, electrophysiological and computational approaches to investigate activity propagation and information processing in the cerebral cortex.
2000, 2006
Specialist in anatomy and professor with a joint appointment at the Vogt Brain Research Institute and the Institute of Anatomy II.
2006 Guest professor at the East China Univ. of Science and Technology, Shanghai.
 
Funding
 
  Wellcome Trust collaboration grant (with Malcolm Young, University of Newcastle)
EU Thematic network "Computational Neuroscience" (coordinated by Erik De Schutter)
DFG ("Algorithmic analysis of neural connectivity" with Egon Wanke; Graduate School 320 AG Kötter/Zilles)
Boehringer Ingelheim Foundation ("Brain connectivity" workshops with Karl Friston and Pedro Valdes-Sosa)
NRW Research Exchange for Sweden (with Per Roland)
J.S McDonnell Foundation (Brain Network Recovery Group led by Randy McIntosh)
 
Editorial Boards
 
  Cognitive Neurodynamics
International Journal of Neural Systems
Neurocomputing
Neuroinformatics
PLoS Computational Biology
Brain Structure and Function
Frontiers in Neuroinformatics (assoc. ed.)
 
Memberships
 
  Neuroinformatics Committee of the Society for Neuroscience
External Advisory Board of the Neuroinformatics Doctoral Training Centre, Univ. of Edinburgh
 
publications top
   
See Publications section