|Our group coordinates and participates in several Neuroscience courses for different curricula of the Medical (UMCN) as well as Science faculty (FNWI)|
For questions regarding participation, content or organization, please contact the coordinator Dr. Schubert:
|MOL021 Project: Cellbiophysics|
Aim of the “project cellbiophysics” is to introduce students of molecular life-sciences to fundamental cell biophysics, by means of bioelectricity. Bioelectricity in based on unequal distributions of ions (ion gradients) over a cell’s membrane. Due to the membrane’s specific and selective ion permeability these gradients can generate a membrane potential. The membrane of excitable cells, such as neurons or muscle cells contains voltage dependent ion channels, which enable the cells to generate action potentials – the core of signal transmission in neural networks and controlled muscle activity. In this course we will discuss the different cell-physiological and biophysical properties that underlie the membrane potential of cells and the generation and transmission of action potential. We will furthermore discuss the specific role and function of ion channels in regulating the membrane potential and excitability of cells. Eventually the students will use the acquired knowledge for interpreting molecular life-science related problems, specifically the physiology and pathophysiology of muscle cells. Here we will focus on the partially severe muscular dysfunctions: skeletal muscle channelopathies.
|5KNW9 Translationele Neuroscience|
|- 3rd year Medicine, UMCN, elective course
- March-April, every 2nd year, in Dutch
Waarom is er nog steeds geen middel tegen aandoeningen van de van de hersenen zoals Parkinson, hoewel die ziekte al decennia intensief bestudeerd wordt? Welke mogelijkheden voor therapieën worden er op dit moment gebruikt of onderzocht? Dit is de kernvragen van transnationale neurowetenschappen. Het begrip “translationeel” slaat op de overdracht van kennis tussen het onderzoek in de neurowetenschappen en de klinische praktijk. De neurowetenschappen maken op dit moment een snelle ontwikkeling door. De resultaten van het onderzoek vinden snel hun weg in de klinische praktijk. Andersom leiden de ervaringen in de kliniek weer tot nieuwe wetenschappelijke inzichten. In dit blok zullen zowel het onderzoek als de klinische praktijk aan bod komen, en de onderlinge bevruchting van deze twee.
|MIN16 Translational Neuroscience|
|- New 3rd year Biomedical Science Minor, UMCN
- Starts Sept 2015, 20 weeks 2 days per week, in English
Why are there still no cures even for intensively studied neurodevelopmental and movement
disorders, such as autism spectrum disorders? Starting from this basic question you are going to set a
framework in this interfaculty minor “Translational Neuroscience” and draw upon the following topics:
What is currently known about the neurobiological mechanisms underlying these disorders – and what
is not known? What state of the art scientific tools do we have to investigate these disorders? Where
is preclinical and clinical research now and are there new treatments and therapies in sight? The
problems clinicians and researchers nowadays face with neurodevelopmental and movement
disorders range from diagnostics, neurobiology, genetics and research methodologies to therapy.
Aim of this course is to enable you to apply the current knowledge in molecular, cellular and
behavioral neurobiology to propose translational research strategies. This will enable you to better
understand the etiology of neurological disorders and their potential treatments.
|BB063B Neuroscience: From Basics to Clinics|
- 3rd year Medical Biology, elective course, FNWI
- Sept -Nov, in English
How much is really known about single neurons, neural networks or the functions of the brain? How far is research in terms of treatment of severe neuronal diseases? What are the state of the art methods currently used in the laboratories worldwide for untangling the complex questions of neuroscience? These are the key questions that will be addressed and discussed during this course. The course will make use of most recent literature and the expertise of active researchers to give a detailed view of neuronal functions, cortical connectivity and pathophysiology of the brain. Furthermore, instead of just presenting facts, the research methodologies that stand behind the different findings will be explained and partially also demonstrated.